Journal
Discover Oncology
Discover Oncology is an open access journal publishing content that interfaces at all levels of cancer research.
Cancers such as lung, pancreatic, and colon often present minimal symptoms in their early stages, making early detection challenging. The deep anatomical location of organs like the lungs and pancreas further complicates traditional detection methods. As a result, many cancers are diagnosed at advanced stages, where treatment options are limited and less effective. This underscores the critical need for novel strategies to detect and treat these cancers at an earlier stage.
Recent research has highlighted the potential of extracellular vesicles (EVs) and circulating EV-carrying nucleic acids as powerful tools in the fight against cancer. These technologies show promise not only in early detection and prognosis but also in engineering EVs as targeted therapeutic agents designed to attack cancer cells directly. The development of such strategies is expected to significantly impact the future of cancer treatment.
This collection invites studies and research that explore the application of EVs and circulating EV nucleic acids in cancer research, with a focus on improving early detection, enhancing treatment efficacy, and ultimately improving patient outcomes in lung, pancreatic, and colon cancers.
Submit your manuscript to this collection through the participating journal.
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Joyce Huanhuan Chen
Assistant Professor, Molecular Engineering and Cancer Research, University of Chicago, United States. She earned her PhD from Cornell University and has received numerous prestigious grants and awards, including NSF Fellowships, the NCI PS-OC Young Investigator Award, Beckman Foundation Fellowships, the NIH K99/R00 Pathway to Independence Award, and the DoD Idea Development Award. Prof. Chen has published extensively in leading journals such as Nature, Cell Stem Cell, and the Journal of Clinical Investigation. -
Kui Zhang
PhD, University of Chicago, United States. He received his bachelor's and doctoral degree in Animal Science from the Southwest University of China. In his Ph.D., his research is focused on innate immune with the animal model, including differentiation and regulation of hematopoietic stem cells. In addition, He is also interested in natural compounds in cancer therapy, including deep exploring the application of traditional medicine using the mouse tumor model and its mechanism. He will be studying the small cell lung cancer initiation and metastasis using a pluripotent stem cells-derived tumour model. -
Abhimanyu Thakur
PhD, University of Chicago, United States. Dr. Abhimanyu Thakur earned his PhD in Biomedical Sciences from the City University of Hong Kong, focusing on exosomal cargoes as biomarkers in glioma. He later contributed to the Center for Regenerative Medicine & Health and worked with Prof. Joyce Chen at the University of Chicago on exosomes in lung neuropathology. His research spans stem cell and exosome bioengineering, cancer research, biosensing, drug delivery, and machine learning in biomedicine. He has received prestigious awards, including the Young Investigator Award and the Global Young Scientists Award.
