Journal of Mammary Gland Biology and Neoplasia is the leading journal in the field of mammary gland biology that provides researchers within and outside the field with an integrated...
The topical collection aims to highlight the critical role of lineage tracing techniques in advancing our understanding of mammary gland development, function, and pathology, particularly in the context of breast cancer. This collection seeks to bring together pioneering research that uses lineage tracing to map cell fate, lineage relationships, and the dynamics of cell populations within the mammary gland. We invite original research articles, comprehensive reviews, and insightful perspectives that delve into the use of lineage tracing in normal mammary gland biology, the identification of mammary stem and progenitor cells, and the mechanisms of tissue homeostasis and regeneration. Additionally, studies that employ lineage tracing to uncover the cellular origins and evolution of breast cancer, track tumor progression, and understand the heterogeneity of cancer cell populations are highly encouraged. This collection aims to provide a platform for the latest advancements in lineage tracing technologies and their application in unraveling the complexities of mammary gland biology and breast cancer. By showcasing innovative research in this field, we aim to foster a deeper understanding of mammary gland dynamics and breast cancer, ultimately contributing to the development of more effective diagnostic and therapeutic strategies.
This collection supports United Nations Sustainable Development Goals 3: Good Health & Well-BeingSubmit your manuscript to this collection through the participating journal.
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Alexandra Van Keymeulen, PhD
Alexandra Van Keymeulen received her PhD in Sciences from Université Libre de Bruxelles (ULB) in 2000. She then joined the Henry Bourne Lab at UCSF as a postdoctoral fellow, where she has been working on chemotaxis signaling pathways. Alexandra started her own research team at ULB, within the Laboratory of Stem Cells and Cancer, headed by Cédric Blanpain, in 2008, when she was appointed to a FNRS tenure position. The research of her group focuses on deciphering the cell hierarchy, the cell identities and cell communications in the mammary gland, as well as the cell of origin of breast cancer, cancer progression and tumour heterogeneity.
