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Resolvins in resolution of Inflammation

Participating journal: Journal of Inflammation

Resolution of inflammation is an essential endogenous process that protects host tissues from a chronic inflammatory response. Resolution of inflammation is an active process, regulated by biochemical mediators and receptor-signaling pathways and driven by specialized pro-resolving mediators (SPM) derived from poly-unsaturated fatty acids (PUFA), including lipoxins, resolvins, (E and D series) protectins and maresins. In this collection we will discuss the crosstalk between resolution signals in the tissue response to injury has therapeutic application potential for preventing, maintaining, and regenerating chronically damaged tissues. These pathways may provide novel therapeutic protocols for autoimmune and autoinflammatory diseases, infection and trauma via regulation of cytokines, leucocyte trafficking and function.

This Collection supports and amplifies research related to SDG 3, Good Health and Well-Being.

Participating journal

Submit your manuscript to this collection through the participating journal.

Exploring the full spectrum of inflammation, encompassing molecular, cellular, animal and clinical studies and related aspects of pharmacology, such as anti-inflammatory drug...

Editors

  • Graham Wallace, PhD, University of Birmingham, United Kingdom

    Graham Wallace is a Senior Lecturer in the Institute of Inflammation and Ageing. Graham has published over 75 research papers in scientific journals as well as reviews in the fields of ocular immunology, Behcet’s Disease and immunogenetics. He has received grants from Guide Dogs for the Blind Association, Fight for Sight, and the Wellcome Trust. He is an enthusiastic communicator on the theme immune responses in the eye and the effects of gene polymorphgisms on ocular diseases. Graham is on the Medical Panel of the Behcet’s Syndrome Society and speaks at meetings of patient groups on a regular basis.

Articles

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